50": A well worked move by Berry and Uche Ikpeazu resulted in goal scorer Dunk's cross evading everybody for Cambridge.
48": A great cross on the right win from Gavin Massey is well handled by Norris.
Cambridge get the second half underway.
Both sets of players return to the pitch ready for the second 45 minutes. Are we about to see a great comeback from the O's?
Do you think Edwards should make any changes at half-time?
Half-Time: Leyton Orient 0-1 Cambridge United.
"44: The main problem for Orient is losing possession in the final third and gifting Cambridge the opportunity to attack them. A bit more quality in the opposition's half is needed. A minimum of three added minutes is branded by Fourth Official Geoffrey Russell.
39": A dangerous cross from Piero Mingoia if flicked behind by Collins for a Cambridge corner, but the visitors keep hounding the O's box as the hosts manage to clear their lines.
35": Cambridge's danger man so far has been Luke Berry. Is underrated strength and skill is causing havoc to the Orient defence. The likes of Parkes, and even Collins need to get tighter to the playmaker.
31": Defender Teddy Mezague will be substituted as the Frenchman is forced off with a groin injury. Yvan Erichot replaces him.
28": A snap shot from Berry from just outside the area falls straight into the hands of Cisak.
27": A corner and a lofted cross into the Cambridge box is dealt with, but Orient need to produce more of that on a more frequent basis.
24": The away side keeping the ball well and are making the home side chase the ball on every occasion. The intent of going in at half-time 1-0 up is there for Cambridge. Just one moment of quality from Orient is all that is needed.
22": A free kick to Cambridge is eventually cleared, but the O's are now on edge since going 1-0 down.
A scramble in the O's box saw Luke Berry's shot saved, before Harrison Dunk pounced on a loose ball and finished with ease.
18": Two great chances for the hosts. First, Hunt went close with a half volley from 25 yards out, before Sandro Semedo's left footed strike was well saved.
The O's are currently using a 4-4-2 formation at the moment, with McCallum and 17 year old Sam Dalby as the strikers, and Captain Nicky Hunt continuing his stint at left back, as the home side shot towards The Tommy Johnston Stand.
7": At the other end, Luke Berry's cross almost creeps past Alex Cisak, but the O's shot stopper had it covered.
5": A whipped Collins free kick saw Tom Parkes in acres of space, but the centre half's search for his first goal for the club continues as his header falls straight into the hands of Will Norris.
3": Both teams are still trying to settle into the game with no chances created yet.
Michael Collins gets the game underway.
Both sets of players will take to the field very shortly.
However, Orient will be looking for revenge from the last time they met United at Brisbane Road. A brace from Ben Williamson and a Jimmy Spencer goal secured a 3-1 win after Armand Gnanduillet netted for the O's.
Both teams now head down the tunnel preparing for the 13:00 kick-off.
This could be the toughest game of the season so far for Orient, considering that the visitors have won five successive games, the longest in League Two so far.
Orient are now into their warm-up as we only have to wait half an hour more for the much anticipated kick-off. Who is excited about this game?
Hunt said: "The confidence is coming back at home and if we start off well in the first 10-15 minutes then I don't think any team in the division will cope with us. I am sure you can all see the hard work and endeavour we are putting in throughout the week in training and hopefully that will help us get more home wins."
Meanwhile veteran defender Nicky Hunt has expressed his eagerness for the side to maintain a good home record going into 2017.
Edwards said: "The timing seems to see us come up against sides when they are in-form and that is what we have this afternoon against Cambridge United. Wycombe remain in good form and even Crawley had gone into the game against us on the back of two wins and I am sure Shaun Derry's side will be full of confidence going into the match."
Edwards gave his pre-match thoughts ahead of today's game and warned Cambridge will be tough opposition.
The Cambridge players arrive on the pitch for their warm-up and are greeted with a strong away following.
The team news is in and Orient are unchanged from the home win against Crawley.
Leyton Orient back-to-back home wins for the first time this season.